Article
Reducing cryptic relatedness in genomic data sets via a central node exclusion algorithm.
Molecular ecology resources - 1 May 2018
Fonseca Pablo A S, Leal Thiago P, Santos Fernanda C, Gouveia Mateus H, Id-Lahoucine Samir, Rosse Izinara C, Ventura Ricardo V, Bruneli Frank A T, Machado Marco A, Peixoto Maria Gabriela C D, Tarazona-Santos Eduardo, Carvalho Maria Raquel S
Abstract excerpt
Cryptic relatedness is a confounding factor in genetic diversity and genetic association studies. Development of strategies to reduce cryptic relatedness in a sample is a crucial step for downstream genetic analyses. This study uses a node selection algorithm, based on network degrees of centrality, to evaluate its applicability and impact on evaluation of genetic diversity and population stratification. 1,036...
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