Article
Shared cancer neoantigens: Making private matters public.
The Journal of experimental medicine - 2 Jan 2018
Klebanoff Christopher A, Wolchok Jedd D
Abstract excerpt
In this issue of JEM, Chheda et al. (https://doi.org/10.1084/jem.20171046) report that a conserved hotspot mutation associated with an aggressive form of brain cancer generates an immunogenic T cell epitope restricted by a common HLA subtype, thereby creating a "public" neoantigen.
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
