Article
Combinations of genetic variants associated with bipolar disorder.
PloS one - 1 Jan 2017
Mellerup Erling, Andreassen Ole A, Bennike Bente, Dam Henrik, Djurovic Srdjan, Jorgensen Martin Balslev, Kessing Lars Vedel, Koefoed Pernille, Melle Ingrid, Mors Ole, Moeller Gert Lykke
Abstract excerpt
The main objective of the study was to find genetic variants that in combination are significantly associated with bipolar disorder. In previous studies of bipolar disorder, combinations of three and four single nucleotide polymorphisms (SNP) genotypes taken from 803 SNPs were analyzed, and five clusters of combinations were found to be significantly associated with bipolar disorder. In the present study,...
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