Article
The prothrombotic state in paroxysmal nocturnal hemoglobinuria: a multifaceted source.
Haematologica - 1 Jan 2018
Peacock-Young Barnaby, Macrae Fraser L, Newton Darren J, Hill Anita, Ariëns Robert A S
Abstract excerpt
Paroxysmal nocturnal hemoglobinuria is a rare acquired hematologic disorder, the most serious complication of which is thrombosis. The increased incidence of thrombosis in paroxysmal nocturnal hemoglobinuria is still poorly understood, but unlike many other thrombotic disorders, predominantly involves complement-mediated mechanisms. This review article discusses the different factors that contribute to the...
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