Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Paroxysmal Nocturnal Hemoglobinuria: Biology and Treatment

6 Sept 2023

Abstract excerpt

Paroxysmal nocturnal hemoglobinuria (PNH) is a nonmalignant clonal hematopoietic disorder characterized by the lack of glycosylphosphatidylinositol-anchored proteins (GPI-APs) as a consequence of somatic mutations in the phosphatidylinositol glycan anchor biosynthesis class A (PIGA) gene. Clinical manifestations of PNH are intravascular hemolysis, thrombophilia, and bone marrow failure. Treatment of PNH mainly...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Complement system in diseases
Share to Hemoglobinopathies and Related Disorders
Share to Renal Diseases and Glomerulopathies

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 37763731
DOI: 10.3390/medicina59091612

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 23 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Paroxysmal Nocturnal Hemoglobinuria: Biology and TreatmentPMID 37763731Read ↗

Paroxysmal Nocturnal Hemoglobinuria: Unraveling Its Molecular Pathogenesis and Advancing Targeted Therapeutic StrategiesSemantic proximity Read ↗

[Paroxysmal nocturnal hemoglobinuria: from physiopathology to treatment].Semantic proximity Read ↗

Update on the diagnosis and management of paroxysmal nocturnal hemoglobinuriaSemantic proximity Read ↗

Paroxysmal nocturnal hemoglobinuria.Semantic proximity Read ↗

Recent advances in the pathogenesis and treatment of paroxysmal nocturnal hemoglobinuriaSemantic proximity Read ↗

Paroxysmal nocturnal hemoglobinuria: current issues in pathophysiology and treatment.Semantic proximity Read ↗

The pathophysiology of disease in patients with paroxysmal nocturnal hemoglobinuria.Semantic proximity Read ↗

Paroxysmal nocturnal haemoglobinuria.Semantic proximity Read ↗

Paroxysmal nocturnal hemoglobinuria from bench to bedside.Semantic proximity Read ↗

[Paroxysmal nocturnal hemoglobinuria].Semantic proximity Read ↗

Paroxysmal Nocturnal Hemoglobinuria as a Molecular DiseaseSemantic proximity Read ↗

New insights into paroxysmal nocturnal hemoglobinuria.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.