Article
Diagnostic markers for the detection of ovarian cancer in BRCA1 mutation carriers.
PloS one - 1 Jan 2017
Gschwantler-Kaulich Daphne, Weingartshofer Sigrid, Rappaport-Fürhauser Christine, Zeillinger Robert, Pils Dietmar, Muhr Daniela, Braicu Elena I, Kastner Marie-Therese, Tan Yen Y, Semmler Lorenz, Sehouli Jalid, Singer Christian F
Abstract excerpt
BACKGROUND: Screening for ovarian cancer (OC) in women at high risk consists of a combination of carbohydrate antigen 125 (CA125) and transvaginal ultrasound, despite their low sensitivity and specificity. This could be improved by the combination of several biomarkers, which has been shown in average risk patients but has not been investigated until now in female BRCA mutation carriers. METHODS: Using a...
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