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Article

Impact of maternal high fat diet on hypothalamic transcriptome in neonatal Sprague Dawley rats.

PloS one - 1 Jan 2017

Barrand Sanna, Crowley Tamsyn M, Wood-Bradley Ryan J, De Jong Kirstie A, Armitage James A

Abstract excerpt

Maternal consumption of a high fat diet during early development has been shown to impact the formation of hypothalamic neurocircuitry, thereby contributing to imbalances in appetite and energy homeostasis and increasing the risk of obesity in subsequent generations. Early in postnatal life, the neuronal projections responsible for energy homeostasis develop in response to appetite-related peptides such as...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 29240779
DOI: 10.1371/journal.pone.0189492
PMCID: PMC5730210

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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