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Article

BTG2 is a tumor suppressor gene upregulated by p53 and PTEN in human bladder carcinoma cells.

Cancer medicine - 1 Jan 2018

Tsui Ke-Hung, Chiang Kun-Chun, Lin Yu-Hsiang, Chang Kang-Shuo, Feng Tsui-Hsia, Juang Horng-Heng

Abstract excerpt

Although widely deemed as a tumor suppressor gene, the role of B-cell translocation gene 2 (BTG2) in bladder cancer is still inconclusive. We investigated the role and regulatory mechanism of BTG2 in bladder cancer. BTG2 expression in human bladder tissues was determined by RT-qPCR and immunoblotting assays. Expressions of BTG2 and PTEN in bladder carcinoma cells were determined by immunoblotting, RT-qPCR, or...

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Identifiers

PMID: 29239139
DOI: 10.1002/cam4.1263
PMCID: PMC5773943

Genes

BTG2
PTEN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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