Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The suppressing effects of BTG3 expression on aggressive behaviors and phenotypes of colorectal cancer: An in vitro and vivo study.

Oncotarget - 14 Mar 2017

Zheng Hua-Chuan, He Hao-Yu, Wu Ji-Cheng, Li Jing, Zhao Shuang, Zhao Gui-Feng, Jiang Hua-Mao, Yu Xue-Wen, Li Zhi-Jie

Abstract excerpt

Here, we found that down-regulated expression of BTG3 might be positively correlated with colorectal carcinogenesis and its overexpression suppressed proliferation, glycolysis, mitochondrial respiration, cell cycle progression, migration, and invasion, and induced apoptosis, senescence and differentiation in SW480 and SW620 cells. After treated with cisplatin, MG132, paclitaxel and SAHA, BTG3 transfectants...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Cycle Proteins
Share to Cell Line, Tumor

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cell Proliferation

Share to Colorectal Neoplasms

Share to DNA-Binding Proteins

Share to Genetic Therapy

Share to Nuclear Proteins

Share to Transfection

Source

Open in PubMed Open full text

Identifiers

PMID: 28407690
DOI: 10.18632/oncotarget.15438
PMCID: PMC5392331

Genes

BTG3
ATG14
XIAP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The suppressing effects of BTG3 expression on aggressive behaviors and phenotypes of colorectal cancer: An in vitro and vivo study.PMID 28407690Read ↗

The roles of BTG3 expression in gastric cancer: a potential marker for carcinogenesis and a target molecule for gene therapy.Semantic proximity Read ↗

Identification of GSPT1 as prognostic biomarker and promoter of malignant colon cancer cell phenotypes via the GSK-3β/CyclinD1 pathway.Semantic proximity Read ↗

MDFI promotes the proliferation and tolerance to chemotherapy of colorectal cancer cells by binding ITGB4/LAMB3 to activate the AKT signaling pathwaySemantic proximity Read ↗

BAG3 regulates cell proliferation, migration, and invasion in human colorectal cancerSemantic proximity Read ↗

CTSG Suppresses Colorectal Cancer Progression through Negative Regulation of Akt/mTOR/Bcl2 Signaling PathwaySemantic proximity Read ↗

Overexpression of GSTP1 promotes colorectal cancer cell proliferation, invasion and metastasis by upregulating STAT3Semantic proximity Read ↗

GTSE1 is involved in breast cancer progression in p53 mutation-dependent mannerSemantic proximity Read ↗

CSTB accelerates the progression of hepatocellular carcinoma via the ERK/AKT/mTOR signaling pathwaySemantic proximity Read ↗

Glutathione peroxidase 3 (GPX3) expression predicts the prognosis of numerous malignant tumors: A pan-cancer AnalysisSemantic proximity Read ↗

Overexpression of GSTP1 promotes colorectal cancer cell proliferation, invasion and metastasis by up-regulating STAT3Semantic proximity Read ↗

LACTB Regulates PIK3R3 to Promote Autophagy and Inhibit EMT and Proliferation Through the PI3K/AKT/mTOR Signaling Pathway in Colorectal CancerSemantic proximity Read ↗

Establishment and characterization of a novel highly aggressive gallbladder cancer cell line, TJ-GBC2Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.