Article

FATP2 activates PI3K/Akt/mTOR pathway by inhibiting ATF3 and promotes the occurrence and development of bladder cancer

2024-01-08

Abstract excerpt

Bladder cancer (BLCA) is ranked among the main causes of mortality in male cancer patients, and research into targeted therapies guided by its genomics and molecular biology has been a prominent focus in BLCA studies. Fatty acid transporter protein 2 (FATP2/SLC27A2), a member of the FATPs/SLC27As family,is a key contributor to the progression of cancers such as hepatocellular carcinomas and melanomas.However,its r...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 9e44cad7-3840-506b-9ef3-05fdd2bab9d9
DOI: 10.21203/rs.3.rs-3827634/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

FATP2 activates PI3K/Akt/mTOR pathway by inhibiting ATF3 and promotes the occurrence and development of bladder cancerDOI 10.21203/rs.3.rs-3827634/v1Read

RNA-seq reveals novel mechanistic targets of Livin in bladder cancerSemantic proximity Read

Ubiquitin-like protein FAT10 promotes bladder cancer progression by stabilizing survivinSemantic proximity Read

The Long Non-coding RNA TMPO-AS1  Promotes Bladder Cancer Growth and Progression via OTUB1-induced E2F1 DeubiquitinationSemantic proximity Read

Upregulated SMYD3 promotes bladder cancer progression by targeting BCLAF1 and activating autophagySemantic proximity Read

RRM2 Is a Putative Biomarker and Promotes Bladder Cancer Progression via PI3K/AKT/mTOR PathwaySemantic proximity Read

DARS2 Promotes Bladder Cancer Progression by Enhancing PINK1-Mediated MitophagySemantic proximity Read

Unraveling FATP1, regulated by ER-β, as a targeted breast cancer innovative therapySemantic proximity Read

PSMD2 promotes the progression of bladder cancer and is correlated with immune infiltrationSemantic proximity Read

Research on the fatty acid metabolism gene FN1 and establishment of a model to guide immunotherapy of bladder cancerSemantic proximity Read

Effects and mechanisms of AMIGO2 in proliferation, migration and drug resistance of bladder cancerSemantic proximity Read

Phosphorylation of TFCP2L1 by CDK1 is required for stem cell pluripotency and bladder carcinogenesisSemantic proximity Read

Potential of APOBEC3B as a therapeutic target and its role in bladder cancer onset and progressionSemantic proximity Read