Article
Genome-wide association study of delay discounting in 23,217 adult research participants of European ancestry.
Nature neuroscience - 1 Jan 2018
Sanchez-Roige Sandra, Fontanillas Pierre, Elson Sarah L, Pandit Anita, Schmidt Ellen M, Foerster Johanna R, Abecasis Gonçalo R, Gray Joshua C, de Wit Harriet, Davis Lea K, MacKillop James, Palmer Abraham A
Abstract excerpt
Delay discounting (DD), the tendency to discount the value of delayed versus current rewards, is elevated in a constellation of diseases and behavioral conditions. We performed a genome-wide association study of DD using 23,127 research participants of European ancestry. The most significantly associated single-nucleotide polymorphism was rs6528024 (P = 2.40 × 10-8), which is located in an intron of the gene...
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