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Article

DHA supplementation prevent the progression of NASH via GPR120 signaling.

European journal of pharmacology - 5 Feb 2018

Nakamoto Kazuo, Shimada Koki, Harada Shinichi, Morimoto Yasuko, Hirasawa Akira, Tokuyama Shogo

Abstract excerpt

Nonalcoholic steatohepatitis (NASH) is one of the most common liver diseases involving chronic accumulation of fat and inflammation, often leading to advanced fibrosis, cirrhosis and carcinoma. However, the pathological mechanism for this is unknown. GPR120/FFAR4 has been recognized as a functional fatty acid receptor and an attractive therapeutic target for metabolic diseases. In this study, we investigated the...

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Share to Diet, High-Fat
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Docosahexaenoic Acids

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Share to Non-alcoholic Fatty Liver Disease

Share to Receptors, G-Protein-Coupled

Source

Identifiers

PMID: 29221950
DOI: 10.1016/j.ejphar.2017.11.046

Genes

FFAR4
TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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