Article
Cancer Stem Cell-Suppressing Activity of Chrysotoxine, a Bibenzyl from Dendrobium pulchellum.
The Journal of pharmacology and experimental therapeutics - 1 Feb 2018
Bhummaphan Narumol, Pongrakhananon Varisa, Sritularak Boonchoo, Chanvorachote Pithi
Abstract excerpt
Cancer stem cells (CSCs) have been recognized as rare populations driving cancer progression, metastasis, and drug resistance in leading cancers. Attempts have been made toward identifying compounds that specifically target these CSCs. Therefore, investigations of novel therapeutic strategies for CSC targeting are required. The cytotoxic effects of chrysotoxine on human non-small cell lung cancer-derived H460 and...
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