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Article

Salmonella small RNA fragment Sal-1 facilitates bacterial survival in infected cells via suppressing iNOS induction in a microRNA manner.

Scientific reports - 5 Dec 2017

Zhao Chihao, Zhou Zhen, Zhang Tianfu, Liu Fenyong, Zhang Chen-Yu, Zen Ke, Gu Hongwei

Abstract excerpt

Salmonella can hijack host atypical miRNA processing machinery to cleave its small non-coding RNA into a ~22-nt RNA fragment, Sal-1, which facilitates Salmonella survival in the infected host. The mechanism through which Sal-1 promotes Salmonella survival, however, remains unknown. In the present study, we reported that Sal-1 targets cellular inducible nitric oxide synthase (iNOS) in a miRNA manner, leading to...

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Identifiers

PMID: 29208934
DOI: 10.1038/s41598-017-17205-4
PMCID: PMC5717148

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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