Article
Transcriptome-wide association study revealed two novel genes associated with nonobstructive azoospermia in a Chinese population.
Fertility and sterility - 1 Dec 2017
Jiang Tingting, Wang Yuzhuo, Zhu Meng, Wang Yifeng, Huang Mingtao, Jin Guangfu, Guo Xuejiang, Sha Jiahao, Dai Juncheng, Hu Zhibin
Abstract excerpt
OBJECTIVE: To investigate the associations between genetically cis-regulated gene expression levels and nonobstructive azoospermia (NOA) susceptibility. DESIGN: Transcriptome-wide association study (TWAS). SETTING: Medical university. INTERVENTIONS: None. MAIN OUTCOME MEASURE(S): The cis-hg2 values for each gene were estimated with GCTA software. The effect sizes of cis-single-nucleotide polymorphisms (SNPs) on...
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