Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Essential Role of IFT140 in Promoting Dentinogenesis.

Journal of dental research - 1 Apr 2018

Li G, Liu M, Zhang S, Wan H, Zhang Q, Yue R, Yan X, Wang X, Wang Z, Sun Y

Abstract excerpt

Primary cilia, with highly regulated cellular sensory functions, play key roles in tissue development and function maintenance. Intraflagellar transport 140 (IFT140) is a subunit of IFT complex A, which is specialized for retrograde transportation in cilia. Mutations of Ift140 are usually associated with syndromic ciliopathy and may cause isolated diseases such as retinal dystrophy, short ribs, and polycystic...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carrier Proteins
Share to Dental Pulp
Share to Fluorescent Antibody Technique

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Immunohistochemistry

Share to Mandible

Share to Mice, Mutant Strains

Share to Real-Time Polymerase Chain Reaction

Share to X-Ray Microtomography

Source

Identifiers

PMID: 29195058
DOI: 10.1177/0022034517741283

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Essential Role of IFT140 in Promoting Dentinogenesis.PMID 29195058Read ↗

Primary cilia and signaling pathways in mammalian development, health and disease.Semantic proximity Read ↗

Canonical and noncanonical intraflagellar transport regulates craniofacial skeletal developmentSemantic proximity Read ↗

Mainzer-Saldino syndrome is a ciliopathy caused by IFT140 mutations.Semantic proximity Read ↗

Deletion of IFT80 Impairs Epiphyseal and Articular Cartilage Formation Due to Disruption of Chondrocyte DifferentiationSemantic proximity Read ↗

Function and regulation of primary cilia and intraflagellar transport proteins in the skeletonSemantic proximity Read ↗

IK is essentially involved in ciliogenesis as an upstream regulator of oral-facial-digital syndrome ciliopathy gene,ofd1Semantic proximity Read ↗

IFT80, which encodes a conserved intraflagellar transport protein, is mutated in Jeune asphyxiating thoracic dystrophy.Semantic proximity Read ↗

Odontogenesis-associated phosphoprotein truncation blocks ameloblast transition into maturation in OdaphC41*/C41* miceSemantic proximity Read ↗

Intraflagellar transport 88 (IFT88) is crucial for craniofacial development in mice and is a candidate gene for human cleft lip and palateSemantic proximity Read ↗

Intraflagellar transporter protein 140 (IFT140), a component of IFT‐A complex, is essential for male fertility and spermiogenesis in miceSemantic proximity Read ↗

An IFT-A protein is required to delimit functionally distinct zones in mechanosensory cilia.Semantic proximity Read ↗

The <i>ift140</i> -Deficient Zebrafish: A Model for Renal Cystogenesis and an F0-Based Screen to Identify Genetic Modifiers of Kidney CystsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.