Article
HIV-1 and hepatitis C virus selection bottleneck in Chinese people who inject drugs.
AIDS (London, England) - 28 Jan 2018
Li Fan, Ma Liying, Feng Yi, Ruan Yuhua, Hu Jing, Song Hongshuo, Liu Pengtao, Ma Jun, Rui Baolin, Kerpen Kate, Scheinfeld Benjamin, Srivastava Tuhina, Metzger David, Li Hui, Bar Katharine J, Shao Yiming
Abstract excerpt
OBJECTIVES: For both HIV-1 and hepatitis C virus (HCV), assessing the stringency of the transmission process is a scientific priority. Enumerations of transmitted/founder (TF) viruses have shown a strict transmission bottleneck in sexual transmission of HIV-1 and a wide range in the multiplicity of infection in HCV. Here, we aim to determine the stringency of parenteral transmission for HIV-1 and HCV in people...
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