Article
Generation and Characterization of HIV-1 Transmitted and Founder Virus Consensus Sequence from Intravenous Drug Users in Xinjiang, China.
AIDS research and human retroviruses - 1 Jun 2017
Li Fan, Ma Liying, Feng Yi, Hu Jing, Ni Na, Ruan Yuhua, Shao Yiming
Abstract excerpt
HIV-1 transmission in intravenous drug users (IDUs) has been characterized by high genetic multiplicity and suggests a greater challenge for HIV-1 infection blocking. We investigated a total of 749 sequences of full-length gp160 gene obtained by single genome sequencing (SGS) from 22 HIV-1 early infected IDUs in Xinjiang province, northwest China, and generated a transmitted and founder virus (T/F virus)...
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