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Article

Genetic- and Lifestyle-dependent Dental Caries Defined by the Acidic Proline-rich Protein Genes PRH1 and PRH2.

EBioMedicine - 1 Dec 2017

Strömberg Nicklas, Esberg Anders, Sheng Nongfei, Mårell Lena, Löfgren-Burström Anna, Danielsson Karin, Källestål Carina

Abstract excerpt

Dental caries is a chronic infectious disease that affects billions of people with large individual differences in activity. We investigated whether PRH1 and PRH2 polymorphisms in saliva acidic proline-rich protein (PRP) receptors for indigenous bacteria match and predict individual differences in the development of caries. PRH1 and PRH2 variation and adhesion of indigenous and cariogenic (Streptococcus mutans)...

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Source

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Identifiers

PMID: 29191562
DOI: 10.1016/j.ebiom.2017.11.019
PMCID: PMC5832611

Genes

PRH1
PRH2
DMBT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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