Article
Using Human 'Experiments of Nature' to Predict Drug Safety Issues: An Example with PCSK9 Inhibitors.
Drug safety - 1 Mar 2018
Jerome Rebecca N, Pulley Jill M, Roden Dan M, Shirey-Rice Jana K, Bastarache Lisa A, R Bernard Gordon, B Ekstrom Leeland, Lancaster William J, Denny Joshua C
Abstract excerpt
INTRODUCTION: When a new drug enters the market, its full array of side effects remains to be defined. Current surveillance approaches targeting these effects remain largely reactive. There is a need for development of methods to predict specific safety events that should be sought for a given new drug during development and postmarketing activities. OBJECTIVE: We present here a safety signal identification...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.