Article
The synergistic effect of nsP2-L618, nsP3-R117, and E2-K187 on the large plaque phenotype of chikungunya virus.
Virus genes - 1 Feb 2018
Thoka Benjawan, Jaimipak Thitigun, Onnome Supachoke, Yoksan Sutee, Ubol Sukathida, Pulmanausahakul Rojjanaporn
Abstract excerpt
Chikungunya virus (CHIKV), a mosquito-borne Alphavirus, is the etiological agent of chikungunya fever. CHIKV re-emerged from 2004 onwards, and subsequently caused major outbreaks in many parts of the world including the Indian Ocean islands, Asia, and the Americas. In this study, a large plaque variant of CHIKV isolated from patient in Thailand was subjected to repeated cycles of plaque-purification in Vero...
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