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Article

Lipid flippases promote antiviral silencing and the biogenesis of viral and host siRNAs in Arabidopsis.

Proceedings of the National Academy of Sciences of the United States of America - 7 Feb 2017

Guo Zhongxin, Lu Jinfeng, Wang Xianbing, Zhan Binhui, Li Wanxiang, Ding Shou-Wei

Abstract excerpt

Dicer-mediated processing of virus-specific dsRNA into short interfering RNAs (siRNAs) in plants and animals initiates a specific antiviral defense by RNA interference (RNAi). In this study, we developed a forward genetic screen for the identification of host factors required for antiviral RNAi in Arabidopsis thaliana Using whole-genome sequencing and a computational pipeline, we identified aminophospholipid...

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Identifiers

PMID: 28123063
DOI: 10.1073/pnas.1614204114
PMCID: PMC5307474

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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