Article
[Association of interleukin-1B gene polymorphisms with coronary heart disease].
Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition - 1 Jan 2009
Zhu Yin-Hua, Xu Yong-Chun, Zhou Bin, Liang Wei-Bo, Wang Yan-Yun, Gao Lin-Bo, Zhang Lin
Abstract excerpt
OBJECTIVE: To determine whether polymorphisms in interleukin-1B gene promoter -31 and exon 5 +3953 loci are associated with coronary heart diseases (CHD) in Chengdu Han population. METHODS: Two SNPs of IL-1B gene (+3953C/T and -31T/C) in 100 patients with CHD (CHD group) and 144 healthy controls in Chengdu were analysed using polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP). RESULTS:...
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