The Hobnail Variant of Papillary Thyroid Carcinoma: Clinical/Molecular Characteristics of a Large Monocentric Series and Comparison with Conventional Histotypes.

doi:10.1089/thy.2017.0248

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Article

The Hobnail Variant of Papillary Thyroid Carcinoma: Clinical/Molecular Characteristics of a Large Monocentric Series and Comparison with Conventional Histotypes.

Thyroid : official journal of the American Thyroid Association - 1 Jan 2018

Watutantrige-Fernando Sara, Vianello Federica, Barollo Susi, Bertazza Loris, Galuppini Francesca, Cavedon Elisabetta, Censi Simona, Benna Clara, Ide Eric Casal, Parisi Alessandro, Nacamulli Davide, Iacobone Maurizio, Pennelli Gianmaria, Mian Caterina

Abstract excerpt

BACKGROUND: The hobnail variant of papillary thyroid carcinoma (HPTC) has an aggressive behavior. The aims of this prospective study were to define the clinical/molecular characteristics of HPTC, and to compare them to those of conventional papillary thyroid carcinoma (PTC). METHODS: From 2010 to 2016, 25 cases of HPTC, characterized clinically and molecularly (BRAF, RAS, TERT promoter, and TP53 mutations), were...

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PMID: 29179638
DOI: 10.1089/thy.2017.0248

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TERT
BRAF

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