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Cytomorphologic and molecular features of hobnail variant of papillary thyroid carcinoma: case series and literature review.

Diagnostic cytopathology - 1 Jan 2014

Asioli Sofia, Maletta Francesca, Pagni Fabio, Pacchioni Donatella, Vanzati Alice, Mariani Sara, Palestini Nicola, Lloyd Ricardo V, Sapino Anna

Abstract excerpt

Recent reports indicate that hobnail papillary thyroid carcinoma (HPTC) is a rare, but very aggressive variant of papillary thyroid carcinoma. The authors describe the cytological features of five HPTC on fine-needle aspiration biopsies (FNAB). Moreover, their immunophenotype and the presence of B-RAF mutation by pyrosequencing were investigated. The patients' (three females and two males) age ranged from 27 to...

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PMID: 23913779
DOI: 10.1002/dc.23028

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