Article
Genetic relatedness of Vibrio cholerae isolates within and between households during outbreaks in Dhaka, Bangladesh.
BMC genomics - 25 Nov 2017
George Christine Marie, Rashid Mahamud, Almeida Mathieu, Saif-Ur-Rahman K M, Monira Shirajum, Bhuyian Md Sazzadul Islam, Hasan Khaled, Mahmud Toslim T, Li Shan, Brubaker Jessica, Perin Jamie, Rahman Zillur, Mustafiz Munshi, Sack David A, Sack R Bradley, Alam Munirul, Stine O Colin
Abstract excerpt
BACKGROUND: Household contacts of cholera patients have a 100 times higher risk of developing a cholera infection than the general population. To compare the genetic relatedness of clinical and water source Vibrio cholerae isolates from cholera patients' households across three outbreaks, we analyzed these isolates using whole-genome-sequencing (WGS) and multilocus variable-number tandem-repeat analysis (MLVA)....
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