Minimal genetic change in Vibrio cholerae in Mozambique over time: Multilocus variable number tandem repeat analysis and whole genome sequencing.

doi:10.1371/journal.pntd.0005671

Article

Minimal genetic change in Vibrio cholerae in Mozambique over time: Multilocus variable number tandem repeat analysis and whole genome sequencing.

PLoS neglected tropical diseases - 1 Jun 2017

Garrine Marcelino, Mandomando Inácio, Vubil Delfino, Nhampossa Tacilta, Acacio Sozinho, Li Shan, Paulson Joseph N, Almeida Mathieu, Domman Daryl, Thomson Nicholas R, Alonso Pedro, Stine Oscar Colin

Abstract excerpt

Although cholera is a major public health concern in Mozambique, its transmission patterns remain unknown. We surveyed the genetic relatedness of 75 Vibrio cholerae isolates from patients at Manhiça District Hospital between 2002-2012 and 3 isolates from river using multilocus variable-number tandem-repeat analysis (MLVA) and whole genome sequencing (WGS). MLVA revealed 22 genotypes in two clonal complexes and...

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Minimal genetic change in Vibrio cholerae in Mozambique over time: Multilocus variable number tandem repeat analysis and whole genome sequencing.

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