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Article

Epigenetic regulation of AXL and risk of childhood asthma symptoms.

Clinical epigenetics - 1 Jan 2017

Gao Lu, Millstein Joshua, Siegmund Kimberly D, Dubeau Louis, Maguire Rachel, Gilliland Frank D, Murphy Susan K, Hoyo Cathrine, Breton Carrie V

Abstract excerpt

Background: AXL is one of the TAM (TYRO3, AXL and MERTK) receptor tyrosine kinases and may affect numerous immune-related health conditions. However, the role for AXL in asthma, including its epigenetic regulation, has not been extensively studied. Methods: We investigated the association between AXL DNA methylation at birth and risk of childhood asthma symptoms at age 6 years. DNA methylation of multiple CpG...

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Share to Asthma
Share to Axl Receptor Tyrosine Kinase

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to CpG Islands

Share to Epigenesis, Genetic

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Share to Proto-Oncogene Proteins

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Source

Open in PubMed Open full text

Identifiers

PMID: 29177020
DOI: 10.1186/s13148-017-0421-8
PMCID: PMC5688797

Genes

AXL
MERTK
TYRO3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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