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Article

EGFR, KRAS, BRAF and HER2 testing in metastatic lung adenocarcinoma: Value of testing on samples with poor specimen adequacy and analysis of discrepancies.

Experimental and molecular pathology - 1 Dec 2017

Forest Fabien, Stachowicz Marie-Laure, Casteillo François, Karpathiou Georgia, Gouzy-Grosjean Fabienne, Guilaubey Colette, Cottier Michèle, Beal Julie, Clemenson Alix, Péoc'h Michel

Abstract excerpt

Molecular testing on metastatic lung adenocarcinoma or on non-small cell non-squamous lung carcinoma often relies on small specimen. In this group of patient with poor specimen adequacy, we analyzed the rate of EGFR, KRAS, BRAF and HER2 mutations compared to their rate in optimal specimen. We analyzed discrepancies in molecular testing results in patients with iterative analysis on several samples. We performed a...

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Source

Identifiers

PMID: 29175303
DOI: 10.1016/j.yexmp.2017.11.013

Genes

KRAS
BRAF
EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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