Article
A proposal for cellularity assessment for EGFR mutational analysis with a correlation with DNA yield and evaluation of the number of sections obtained from cell blocks for immunohistochemistry in non-small cell lung carcinoma.
Journal of clinical pathology - 1 Jul 2016
da Cunha Santos Gilda, Wyeth Tyler, Reid Allie, Saieg Mauro Ajaj, Pitcher Bethany, Pintilie Melania, Kamel-Reid Suzanne, Tsao Ming Sound
Abstract excerpt
AIMS: Different approaches have been described for reporting specimen adequacy for epidermal growth factor receptor (EGFR) mutation analysis. We aimed: (1) to conduct cellularity assessment and to investigate its association with DNA yield, (2) to compare the H&E slides taken before and after the thick sections (curls) obtained for EGFR testing and (3) to evaluate the number of ancillary studies performed....
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