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Real-world data of EGFR mutation testing in Chinese non-small cell carcinoma: Low tumor cell number and tumor cellularity can be accepted.

Pathology, research and practice - 1 Aug 2022

Gu Yajuan, Li Yunlong, Zhao Shunli, Jin Mulan, Lu Jun, Jiang Xingran

Abstract excerpt

INTRODUCTION: Molecular testing on advanced non-small cell lung cancer (NSCLC) often confront of limited specimen.The aim of the study is to compare the mutation frequency in adenocarcinoma samples with poor tumor cell content and the optimal samples, making the optimal strategy of mutation analysis. METHODS: In this retrospective study, mutation status of EGFR, ALK, ROS1, BRAF, KRAS, RET, HER2, CMET, NRAS and...

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PMID: 35700580
DOI: 10.1016/j.prp.2022.153965

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