Article
IDH1 and IDH2 mutations in postoperative diffuse glioma-associated epilepsy.
Epilepsy & behavior : E&B - 1 Jan 2018
Neal Andrew, Kwan Patrick, O'Brien Terence John, Buckland Michael E, Gonzales Michael, Morokoff Andrew
Abstract excerpt
OBJECTIVE: Isocitrate dehydrogenase 1 and 2 mutations (IDH1/2) have an established association with preoperative seizures in patients with grades II-IV diffuse gliomas. Here, we examined if IDH1/2 mutations are a biomarker of postoperative seizure frequency. METHODS: This was a retrospective study. Patients with grades II-IV supratentorial diffuse glioma, immunohistochemistry results of IDH1-R132H, and...
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