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Article

Interaction between DRD2 and lead exposure on the cortical thickness of the frontal lobe in youth with attention-deficit/hyperactivity disorder.

Progress in neuro-psychopharmacology & biological psychiatry - 2 Mar 2018

Kim Johanna Inhyang, Kim Jae-Won, Lee Jong-Min, Yun Hyuk Jin, Sohn Chul-Ho, Shin Min-Sup, Kim Bongseog, Chae Jonghee, Roh Jaewoo, Kim Bung-Nyun

Abstract excerpt

BACKGROUND: The dopamine receptor D2 receptor (DRD2) gene and lead exposure are both thought to contribute to the pathophysiology of attention-deficit/hyperactivity disorder (ADHD). ADHD is characterized by delay in brain maturation, most prominent in the prefrontal cortex (PFC). The D2 receptor is also mainly located in the PFC, and animal studies show that lead exposure affects the dopaminergic system of the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 29169998
DOI: 10.1016/j.pnpbp.2017.11.018

Genes

DRD2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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