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Flotillin scaffold activity contributes to type VII secretion system assembly in Staphylococcus aureus

22 Nov 2017

Abstract excerpt

Scaffold proteins are ubiquitous chaperones that promote efficient interactions between partners of multi-enzymatic protein complexes; although they are well studied in eukaryotes, their role in prokaryotic systems is poorly understood. Bacterial membranes have functional membrane microdomains (FMM), a structure homologous to eukaryotic lipid rafts. Similar to their eukaryotic counterparts, bacterial FMM harbor a...

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PMID: 29166667
DOI: 10.1371/journal.ppat.1006728

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