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Article

Protein complex scaffolding predicted as a prevalent function of long non-coding RNAs.

Nucleic acids research - 25 Jan 2018

Ribeiro Diogo M, Zanzoni Andreas, Cipriano Andrea, Delli Ponti Riccardo, Spinelli Lionel, Ballarino Monica, Bozzoni Irene, Tartaglia Gian Gaetano, Brun Christine

Abstract excerpt

The human transcriptome contains thousands of long non-coding RNAs (lncRNAs). Characterizing their function is a current challenge. An emerging concept is that lncRNAs serve as protein scaffolds, forming ribonucleoproteins and bringing proteins in proximity. However, only few scaffolding lncRNAs have been characterized and the prevalence of this function is unknown. Here, we propose the first computational...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 29165713
DOI: 10.1093/nar/gkx1169
PMCID: PMC5778612

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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