Article
4218T/C polymorphism associations with post-cesarean patient-controlled epidural fentanyl consumption and pain perception.
Acta anaesthesiologica Scandinavica - 1 Mar 2018
Xie W, Zhuang W, Chen L, Xie W, Jiang C, Liu N
Abstract excerpt
BACKGROUND: The utilization of intrathecal opioids is an efficacious component of post-cesarean section pain management. Given that growing evidence indicates that calcitonin gene-related peptide (CGRP) plays a key role in the development of peripheral sensitization and is associated with enhanced pain, we hypothesized that CGRP 4218T/C polymorphism is associated with the variability in fentanyl consumption for...
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