Article
On the origin of obesity: identifying the biological, environmental and cultural drivers of genetic risk among human populations.
Obesity reviews : an official journal of the International Association for the Study of Obesity - 1 Feb 2018
Qasim A, Turcotte M, de Souza R J, Samaan M C, Champredon D, Dushoff J, Speakman J R, Meyre D
Abstract excerpt
Genetic predisposition to obesity presents a paradox: how do genetic variants with a detrimental impact on human health persist through evolutionary time? Numerous hypotheses, such as the thrifty genotype hypothesis, attempt to explain this phenomenon yet fail to provide a justification for the modern obesity epidemic. In this critical review, we appraise existing theories explaining the evolutionary origins of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.