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Article

Structural basis of adaptor-mediated protein degradation by the tail-specific PDZ-protease Prc.

Nature communications - 15 Nov 2017

Su Ming-Yuan, Som Nilanjan, Wu Chia-Yun, Su Shih-Chieh, Kuo Yi-Ting, Ke Lu-Chu, Ho Meng-Ru, Tzeng Shiou-Ru, Teng Ching-Hao, Mengin-Lecreulx Dominique, Reddy Manjula, Chang Chung-I

Abstract excerpt

Peptidoglycan (PG) is a highly cross-linked, protective mesh-like sacculus that surrounds the bacterial cytoplasmic membrane. Expansion of PG is tightly coupled to growth of a bacterial cell and requires hydrolases to cleave the cross-links for insertion of nascent PG material. In Escherichia coli, a proteolytic system comprising the periplasmic PDZ-protease Prc and the lipoprotein adaptor NlpI contributes to PG...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 29138488
DOI: 10.1038/s41467-017-01697-9
PMCID: PMC5686067

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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