Article
mPeriod2 Brdm1 and other single Period mutant mice have normal food anticipatory activity.
Scientific reports - 14 Nov 2017
Pendergast Julie S, Wendroth Robert H, Stenner Rio C, Keil Charles D, Yamazaki Shin
Abstract excerpt
Animals anticipate the timing of food availability via the food-entrainable oscillator (FEO). The anatomical location and timekeeping mechanism of the FEO are unknown. Several studies showed the circadian gene, Period 2, is critical for FEO timekeeping. However, other studies concluded that canonical circadian genes are not essential for FEO timekeeping. In this study, we re-examined the effects of the Per2 Brdm1...
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