Article
Unchanged mitochondrial phenotype, but accumulation of lipids in the myometrium in obese pregnant women.
The Journal of physiology - 1 Dec 2017
Gam Christiane Marie Bourgin Folke, Larsen Lea Hüche, Mortensen Ole Hartvig, Engelbrechtsen Line, Poulsen Steen Seier, Qvortrup Klaus, Mathiesen Elisabeth Reinhart, Damm Peter, Quistorff Bjørn
Abstract excerpt
KEY POINTS: Obesity during pregnancy and childbirth is associated with labour dystocia leading to instrumental or operative delivery, but the underlying pathophysiological mechanisms remain unclear and insufficient uterine contractility has been suggested. This study examined whether reduced myometrial mitochondrial capacity or quantity could contribute as a pathophysiological mechanism to labour dystocia. Data...
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