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Article

Mitochondrial implications in human pregnancies with intrauterine growth restriction and associated cardiac remodelling

2 Apr 2019

Abstract excerpt

Intrauterine growth restriction (IUGR) is an obstetric complication characterised by placental insufficiency and secondary cardiovascular remodelling that can lead to cardiomyopathy in adulthood. Despite its aetiology and potential therapeutics are poorly understood, bioenergetic deficits have been demonstrated in adverse foetal and cardiac development. We aimed to evaluate the role of mitochondria in human...

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PMID: 30941904
DOI: 10.1111/jcmm.14282

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