Article
HIV-1 persistence following extremely early initiation of antiretroviral therapy (ART) during acute HIV-1 infection: An observational study.
PLoS medicine - 1 Nov 2017
Henrich Timothy J, Hatano Hiroyu, Bacon Oliver, Hogan Louise E, Rutishauser Rachel, Hill Alison, Kearney Mary F, Anderson Elizabeth M, Buchbinder Susan P, Cohen Stephanie E, Abdel-Mohsen Mohamed, Pohlmeyer Christopher W, Fromentin Remi, Hoh Rebecca, Liu Albert Y, McCune Joseph M, Spindler Jonathan, Metcalf-Pate Kelly, Hobbs Kristen S, Thanh Cassandra, Gibson Erica A, Kuritzkes Daniel R, Siliciano Robert F, Price Richard W, Richman Douglas D, Chomont Nicolas, Siliciano Janet D, Mellors John W, Yukl Steven A, Blankson Joel N, Liegler Teri, Deeks Steven G
Abstract excerpt
BACKGROUND: It is unknown if extremely early initiation of antiretroviral therapy (ART) may lead to long-term ART-free HIV remission or cure. As a result, we studied 2 individuals recruited from a pre-exposure prophylaxis (PrEP) program who started prophylactic ART an estimated 10 days (Participant A; 54-year-old male) and 12 days (Participant B; 31-year-old male) after infection with peak plasma HIV RNA of 220...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.