Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic Variations in the Fibronectin 1 Gene (FN1) and Risk of Female Reproductive Cancers-A Preliminary Study.

International journal of molecular sciences - 12 May 2026

Pawlik Piotr, Kurzawińska Grażyna, Ożarowski Marcin, Karpiński Tomasz M, Bogacz Anna, Olbromski Piotr J, Mrozikiewicz Aleksandra E, Brązert Maciej, Markwitz Wiesław, Seremak-Mrozikiewicz Agnieszka

Abstract excerpt

We investigated five single-nucleotide variants (SNVs) of the FN1 gene in female reproductive organ cancers. The proteins expressed by this gene are essential components of the extracellular matrix (ECM) that constitutes the tumor microenvironment (TME). The study group included 208 women diagnosed with cervical, uterine, and ovarian cancers and 208 age-matched cancer-free controls. Genomic DNA from whole blood...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Case-Control Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Fibronectins

Share to Genital Neoplasms, Female

Share to Haplotypes

Share to Ovarian Neoplasms

Share to Risk Factors

Share to Uterine Cervical Neoplasms

Source

Open in PubMed Open full text

Identifiers

PMID: 42196282
DOI: 10.3390/ijms27104302
PMCID: PMC13207736

Genes

FN1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic Variations in the Fibronectin 1 Gene (FN1) and Risk of Female Reproductive Cancers-A Preliminary Study.PMID 42196282Read ↗

Role of FN1 and GREB1 gene polymorphisms in endometriosisSemantic proximity Read ↗

Effects of FGFR1 Gene Polymorphisms on the Risk of Breast Cancer and FGFR1 Protein Expression.Semantic proximity Read ↗

Novel breast cancer risk alleles and endometrial cancer risk.Semantic proximity Read ↗

Gene variants polymorphisms and uterine leiomyoma: an updated reviewSemantic proximity Read ↗

An Italian association study and meta-analysis with previous GWAS confirm WNT4, CDKN2BAS and FN1 as the first identified susceptibility loci for endometriosis.Semantic proximity Read ↗

Ninjurin 2 rs118050317 gene polymorphism and endometrial cancer riskSemantic proximity Read ↗

The Association of Flap Endonuclease 1 Genotypes with the Susceptibility of Endometriosis.Semantic proximity Read ↗

The Impact of IGF1 Genetic Variants on Surgical Outcomes and Prognosis in Ovarian CancerSemantic proximity Read ↗

BRCA1 alterations are associated with endometriosis, but BRCA2 alterations show no detectable endometriosis risk: a study in Indian population.Semantic proximity Read ↗

Genetic risk factors for ovarian cancer and their role for endometriosis risk.Semantic proximity Read ↗

Genome-wide association study meta-analysis supports association between MUC1 and ectopic pregnancySemantic proximity Read ↗

Polymorphisms in IL-1A are associated with endometrial cancer susceptibility among Chinese Han population: A case-control study.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.