Article
Role of TLR4 in olfactory-based spatial learning activity of neonatal mice after developmental exposure to diesel exhaust origin secondary organic aerosol.
Neurotoxicology - 1 Dec 2017
Nway Nay Chi, Fujitani Yuji, Hirano Seishiro, Mar Ohn, Win-Shwe Tin-Tin
Abstract excerpt
Exposure to ambient air pollutants has been reported to have various adverse health impacts. Ambient particulate matter comprises primary particles released directly via engine exhaust and secondary organic aerosols (SOAs) formed from oxidative reactions of the ultrafine particle fraction of diesel exhaust (DE). Toll-like receptor 4 (TLR4) is well known to initiate the inflammatory cascade in the central nervous...
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