Article
AhR-deficiency as a cause of demyelinating disease and inflammation.
Scientific reports - 29 Aug 2017
Juricek Ludmila, Carcaud Julie, Pelhaitre Alice, Riday Thorfinn T, Chevallier Aline, Lanzini Justine, Auzeil Nicolas, Laprévote Olivier, Dumont Florent, Jacques Sebastien, Letourneur Frank, Massaad Charbel, Agulhon Cendra, Barouki Robert, Beraneck Mathieu, Coumoul Xavier
Abstract excerpt
The Aryl hydrocarbon Receptor(AhR) is among the most important receptors which bind pollutants; however it also regulates signaling pathways independently of such exposure. We previously demonstrated that AhR is expressed during development of the central nervous system(CNS) and that its deletion leads to the occurrence of a congenital nystagmus. Objectives of the present study are to decipher the origin of these...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.