Conserved brain myelination networks are altered in Alzheimer's and other neurodegenerative diseases.

doi:10.1016/j.jalz.2017.09.012

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Article

Conserved brain myelination networks are altered in Alzheimer's and other neurodegenerative diseases.

Alzheimer's & dementia : the journal of the Alzheimer's Association - 1 Mar 2018

Allen Mariet, Wang Xue, Burgess Jeremy D, Watzlawik Jens, Serie Daniel J, Younkin Curtis S, Nguyen Thuy, Malphrus Kimberly G, Lincoln Sarah, Carrasquillo Minerva M, Ho Charlotte, Chakrabarty Paramita, Strickland Samantha, Murray Melissa E, Swarup Vivek, Geschwind Daniel H, Seyfried Nicholas T, Dammer Eric B, Lah James J, Levey Allan I, Golde Todd E, Funk Cory, Li Hongdong, Price Nathan D, Petersen Ronald C, Graff-Radford Neill R, Younkin Steven G, Dickson Dennis W, Crook Julia R, Asmann Yan W, Ertekin-Taner Nilüfer

Abstract excerpt

INTRODUCTION: Comparative transcriptome analyses in Alzheimer's disease (AD) and other neurodegenerative proteinopathies can uncover both shared and distinct disease pathways. METHODS: We analyzed 940 brain transcriptomes including patients with AD, progressive supranuclear palsy (PSP; a primary tauopathy), and control subjects. RESULTS: We identified transcriptional coexpression networks implicated in...

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PMID: 29107053
DOI: 10.1016/j.jalz.2017.09.012
PMCID: PMC5866744

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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