Article
Experimental miniature piglet model for the infection of human norovirus GII.
Journal of medical virology - 1 Apr 2018
Seo Dong Joo, Jung Day, Jung Soontag, Ha Seung-Kwon, Ha Sang-Do, Choi In-Soo, Myoung Jinjong, Choi Changsun
Abstract excerpt
Ten Yucatan miniature piglets were challenged with the human norovirus (NoV) GII.12/GII.3 CAU140599 strain and five piglets were used as negative controls. Stool, serum, and organs were collected and processed from two NoV-infected piglets and one negative piglet at 1, 2, 3, 5, and 7 days post-inoculation (dpi). NoV was detected in stool and serum samples by real-time RT-PCR. Mild diarrhea was observed at 1-3...
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