Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Median infectious dose of human norovirus GII.4 in gnotobiotic pigs is decreased by simvastatin treatment and increased by age.

The Journal of general virology - 1 Sept 2013

Bui Tammy, Kocher Jacob, Li Yanru, Wen Ke, Li Guohua, Liu Fangning, Yang Xingdong, LeRoith Tanya, Tan Ming, Xia Ming, Zhong Weiming, Jiang Xi, Yuan Lijuan

Abstract excerpt

Human noroviruses (NoVs), a major cause of viral gastroenteritis, are difficult to study due to the lack of a cell-culture and a small-animal model. Pigs share with humans the types A and H histo-blood group antigens on the intestinal epithelium and have been suggested as a potential model for st...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Caliciviridae Infections
Share to Disease Susceptibility

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Germ-Free Life

Share to Hypolipidemic Agents

Share to Intestines

Share to Norovirus

Share to Simvastatin

Share to Viral Load

Source

Open in PubMed Open full text

Identifiers

PMID: 23804568
DOI: 10.1099/vir.0.054080-0
PMCID: PMC3749057

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23804568-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 9 closest

Median infectious dose of human norovirus GII.4 in gnotobiotic pigs is decreased by simvastatin treatment and increased by age.PMID 23804568Read ↗

The effects of simvastatin or interferon-α on infectivity of human norovirus using a gnotobiotic pig model for the study of antivirals.Semantic proximity Read ↗

Virus Shedding and Diarrhea: A Review of Human Norovirus Genogroup II Infection in Gnotobiotic Pigs.Semantic proximity Read ↗

The General Composition of the Faecal Virome of Pigs Depends on Age, but Not on Feeding with a Probiotic BacteriumSemantic proximity Read ↗

Experimental miniature piglet model for the infection of human norovirus GII.Semantic proximity Read ↗

Pathogenesis of an attenuated and a virulent strain of group A human rotavirus in neonatal gnotobiotic pigsSemantic proximity Read ↗

Bile acid-sensitive human norovirus strains are susceptible to sphingosine-1-phosphate receptor 2 inhibitionSemantic proximity Read ↗

A human norovirus-like particle vaccine adjuvanted with ISCOM or mLT induces cytokine and antibody responses and protection to the homologous GII.4 human norovirus in a gnotobiotic pig disease model.Semantic proximity Read ↗

Lessening of porcine epidemic diarrhoea virus susceptibility in piglets after editing of the CMP-N-glycolylneuraminic acid hydroxylase gene with CRISPR/Cas9 to nullify N-glycolylneuraminic acid expressionSemantic proximity Read ↗

Immunization of aged pigs with attenuated pseudorabies virus vaccine combined with CpG oligodeoxynucleotide restores defective Th1 immune responses.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.