Article
Antibiotic perturbation of mixed-strain Pseudomonas aeruginosa infection in patients with cystic fibrosis.
BMC pulmonary medicine - 2 Nov 2017
Tai Anna S, Sherrard Laura J, Kidd Timothy J, Ramsay Kay A, Buckley Cameron, Syrmis Melanie, Grimwood Keith, Bell Scott C, Whiley David M
Abstract excerpt
BACKGROUND: Pulmonary exacerbations in cystic fibrosis (CF) remain poorly understood and treatment is usually targeted at Pseudomonas aeruginosa. Within Australia a predominant shared P. aeruginosa strain (AUST-02) is associated with greater treatment needs. This single centre study assessed temporal shared strain population dynamics during and after antibiotic treatment of exacerbations. METHODS: Sputum was...
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