Article
Pseudomonas aeruginosa adaptation and diversification in the non-cystic fibrosis bronchiectasis lung.
The European respiratory journal - 1 Apr 2017
Hilliam Yasmin, Moore Matthew P, Lamont Iain L, Bilton Diana, Haworth Charles S, Foweraker Juliet, Walshaw Martin J, Williams David, Fothergill Joanne L, De Soyza Anthony, Winstanley Craig
Abstract excerpt
To characterise Pseudomonas aeruginosa populations during chronic lung infections of non-cystic fibrosis bronchiectasis patients, we used whole-genome sequencing to 1) assess the diversity of P. aeruginosa and the prevalence of multilineage infections; 2) seek evidence for cross-infection or common source acquisition; and 3) characterise P. aeruginosa adaptations.189 isolates, obtained from the sputa of 91...
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